Exactly one hundred years ago, two diplomats, one British and one French, concluded the Sykes-Picot agreement, which divided the Middle East into two zones of influence. The agreement became one of the cornerstones of the region, and gave the core area of the Middle East the shape it has assumed since the end of World War I. However, the political order founded a century ago by what were then British and French superpowers, including the regimes created and the borders delineated, is currently under serious challenge. The article looks at the agreement through the lenses of the past and the present, and considers its prospects for surviving the political storms that currently engulf the region. It concludes with one recommendation: Israel should be prepared to articulate its ideas for a solution of the Israeli-Palestinian conflict. When a new „Sykes-Picot“ order is created, it will almost certainly relate to that issue as well.